As long as you’re taking PrEP as prescribed, consuming drugs and alcohol should not directly affect how well PrEP works. However, substance use may affect how consistently you take the medication, and missing doses can lower the effectiveness of PrEP.
And one important note about PrEP and inection drug use: One major study of PrEP use among injection drug users (IDUs) suggests that PrEP may not be as effective at preventing the transmission of HIV through needle, syringe, and drug-works sharing as through sex. The IDUs in the study who reported they were taking PrEP as prescribed and at least had detectable PrEP in their blood had a 74 percent reduced risk of HIV.
#AskTheHIVDoc is a video series from Greater Than AIDS featuring top HIV doctors providing answers to commonly-asked questions about HIV prevention, testing and treatment.
The information and videos provided on this site are for educational purposes and not a substitute for professional medical advice. Always consult your healthcare provider before making any healthcare decisions or for guidance about a specific medical condition.
While we make every effort to keep the medical information on our website updated, we cannot guarantee that the information reflects the most up-to-date research. Also, please note the views expressed by individuals who appear in Greater Than AIDS videos and other content are their own and are not made on behalf of any groups/organizations/associations.